![]() ![]() ![]() Using several case studies, we demonstrate how ChExVis can be used to study channels, extract their properties and gain insights into molecular function. Results from these experiments on several proteins show that ChExVis performance is comparable to, and in some cases, better than existing channel extraction techniques. We apply the method on a number of known channel containing proteins to extract pore features. These methods and the visual analysis framework are implemented in a software tool, ChExVis. We describe methods for effective visualization of the channels and their profiles. The representation also supports efficient computation of channel profiles that help understand channel properties. The method computes geometrically feasible channels, stores both the volume occupied by the channel and its centerline in a unified representation, and reports significant channels. We describe a method for molecular channel extraction based on the alpha complex representation.
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